Primary biliary cholangitis (PBC) is an uncommon, long-term disease of the liver in which the body's immune system mistakenly attacks bile ducts within the liver. This gradually decreases the flow of bile from the liver to the small intestine. A buildup of bile damages and destroys liver tissues.
Primary biliary cholangitis (PBC) is a liver disease that affects the bile ducts that run through your liver. It slowly degrades those bile ducts, making it harder for bile to flow through.
Primary biliary cholangitis (PBC) is an autoimmune disease in which immune cells damage bile ducts, leading to bile buildup that slowly damages the liver. Over time, this can lead to scarring,...
Primary biliary cholangitis (PBC) is a rare liver disease. “Biliary” means bile, which is a digestive fluid that helps your body with digestion and absorbing nutrients. It also helps get rid of...
Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver. [1][2][3] It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis.
Primary Biliary Cholangitis (PBC) is considered an autoimmune disease because of its hallmark serologic signature, antimitochondrial antibody (AMA), and specific bile duct pathology. The etiology of PBC is thought to be due to a combination of genetic risk factors and environmental triggers.
The PBC Foundation offers support to people with PBC, as well as their friends and family. See the support we offer those with PBC.
Primary biliary cholangitis (PBC; previously referred to as primary biliary cirrhosis) is characterized by a T-lymphocyte-mediated attack on small intralobular bile ducts.